Friday, February 6, 2015

3D printed body parts. Thing not of distant future

3D printed body parts. Thing not of distant future

Life extension might just be possible for not all but some of the very elite. Looking forward to most likely hear or even get some organs printed for myself in near future.
Using a combination of cells in what it terms "bio-ink," Organovo already has 3-D-printed blood vessels as well as liver, lung and breast-tumor tissues for laboratory studies of potential treatments for cancer, Parkinson's disease and pulmonary hypertension. Although the company has yet to be profitable since it was incorporated in 2007, it has forged partnerships with several research institutions and drug companies, including giant Hoffman La Roche

A typical process for bioprinting 3D tissues.

3D bioprinting of tissues and organs, Nature Biotechnology 32, 773–785 doi:10.1038/nbt.2958

 Last year an article, "3D bioprinting of tissues and organs", published in Nature Biotechnology, reviewed the 3D bioprinting of living tissues and even organs done so far in research labs around the world. Authors Sean V Murphy & Anthony Atala are researchers at Wake Forest Institute for Regenerative Medicine, USA. They quote, recent advances have enabled 3D printing of biocompatible materials, cells and supporting components into complex 3D functional living tissues. 3D bioprinting is being applied to regenerative medicine to address the need for tissues and organs suitable for transplantation. Compared with non-biological printing, 3D bioprinting involves additional complexities, such as the choice of materials, cell types, growth and differentiation factors, and technical challenges related to the sensitivities of living cells and the construction of tissues. Addressing these complexities requires the integration of technologies from the fields of engineering, biomaterials science, cell biology, physics and medicine. 3D bioprinting has already been used for the generation and transplantation of several tissues, including multilayered skin, bone, vascular grafts, tracheal splints, heart tissue and cartilaginous structures. Other applications include developing high-throughput 3D-bioprinted tissue models for research, drug discovery and toxicology.

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